Noeth, U. and Reichert, J. and Reppenhagen, S. and Steinert, A. and Rackwitz, L. and Eulert, J. and Beckmann, J. and Tingart, M. (2007) Cell based therapy for the treatment of femoral head necrosis. ORTHOPADE, 36 (5). pp. 466-471. ISSN 0085-4530,
Full text not available from this repository. (Request a copy)Abstract
The goal of the therapy for necrosis of the femoral head in adults is the preservation of the femoral head and, therefore, avoidance of total joint replacement. Core decompression is known to reduce the intraosseous pressure and additionally provides the opportunity to introduce bioactive materials, substances and cells into the core tract. These include vascularized and non-vascularized bone grafts, allogenic and synthetic bone substitutes, osteogenic and angiogenic growth factors, as well as different progenitor cells. In particular, the use of cell-based strategies has great therapeutic potential and could play an important role in the treatment of femoral head necrosis in adults in the future. In this article, we summarize the existing clinical experience of current cell-based strategies for the treatment of femoral head necrosis in adults, and present a therapeutic approach using bone marrow stem cells (TRCs: tissue repair cells). in combination with a beta-TCP matrix.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | AVASCULAR NECROSIS; ASEPTIC OSTEONECROSIS; CORE DECOMPRESSION; NEEDLE-BIOPSY; BONE; HIP; TRANSPLANTATION; GRAFT; necrosis of the femoral head; core decompression; stem cells; tissue repair cells (TRCs); beta-TCP |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Orthopädie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2020 09:28 |
| Last Modified: | 14 Dec 2020 09:28 |
| URI: | https://pred.uni-regensburg.de/id/eprint/32853 |
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