Nickel, Marius K. and Loew, Thomas H. and Gil, Francisco Pedrosa (2007) Aripiprazole in treatment of borderline patients, part II: an 18-month follow-up. PSYCHOPHARMACOLOGY, 191 (4). pp. 1023-1026. ISSN 0033-3158,
Full text not available from this repository. (Request a copy)Abstract
Rationale Only one controlled trial is known that employed aripiprazole for patients with borderline personality disorder (BPD). This 8-week trial found significant changes on most scales of the symptom checklist (SCL-90-R), Hamilton depression rating scale (HDRS), Hamilton anxiety rating scale (HARS), and on all scales of the state-trait anger expression inventory (STAXI). Objectives To assess the long-term effectiveness of aripiprazole with multifaceted borderline symptomology, this 18-month follow-up observation with biannual testing was carried out with the same patients from the previous trial (treated with 15-mg aripiprazole daily, n=26, 21 female and 5 male patients; previous placebo group, n=26, 22 female and 4 male patients). Results According to the intent-to-treat principle, significant changes on all scales of the SCL-90-R, HDRS, HARS, and STAXI were observed in the aripiprazole-treated subjects after 18 months. Conclusion Aripiprazole appears to be an effective and relatively safe agent in the long-term treatment of patients with BPD.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ACUTE BIPOLAR MANIA; PERSONALITY-DISORDER; DOUBLE-BLIND; PLACEBO; SCHIZOPHRENIA; EFFICACY; SAFETY; borderline personality disorder; aripiprazole |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Abteilung für Psychosomatische Medizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2020 10:12 |
| Last Modified: | 14 Dec 2020 10:12 |
| URI: | https://pred.uni-regensburg.de/id/eprint/32861 |
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