Surface plasmon resonance biosensor for enrofloxacin based on deoxyribonucleic acid

Cao, Limin and Lin, Hong and Mirsky, Vladimir M. (2007) Surface plasmon resonance biosensor for enrofloxacin based on deoxyribonucleic acid. ANALYTICA CHIMICA ACTA, 589 (1). pp. 1-5. ISSN 0003-2670, 1873-4324

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Abstract

A DNA-based surface plasmon resonance biosensor for enrofloxacin was developed. Heating denatured DNA immobilized on the gold-coated glass surface was exploited. The immobilization was performed by a layer-by-layer co-deposition with a cationic polymer. The sensor performance was tested with real biological probes. Direct and simple determination of enrofloxacin in milk samples was demonstrated. The sensor response obeys Langmuir binding isotherm being almost linear until about 20 mu g mL(-1). The detection limit in milk samples was estimated to be 3 mu g mL(-1). (c) 2007 Elsevier B.V. All rights reserved.

Item Type: Article
Uncontrolled Keywords: ANIMAL PRODUCTS; DNA GYRASE; FLUOROQUINOLONES; RESIDUES; CIPROFLOXACIN; QUINOLONES; BINDING; REACTIVITY; ANTIBODIES; SENSORS; surface plasmon resonance; nucleic acid; biosensor; enrofloxacin; fluoroquinolones; layer-by-layer deposition
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Antje J. Bäumner, formerly Prof. Wolfbeis)
Depositing User: Dr. Gernot Deinzer
Date Deposited: 14 Dec 2020 11:20
Last Modified: 14 Dec 2020 11:20
URI: https://pred.uni-regensburg.de/id/eprint/32878

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