von Landenberg, Philipp and Lehmann, Hartwig W. and Modrow, Susanne (2007) Human parvovirus B19 infection and antiphospholipid antibodies. AUTOIMMUNITY REVIEWS, 6 (5). pp. 278-285. ISSN 1568-9972, 1873-0183
Full text not available from this repository. (Request a copy)Abstract
Erythema infectiosum is the main manifestation of human parvovirus B19 infections. Further B19-related diseases commonly associated with the acute infection are flue-like symptoms, transient aplastic crisis, transient arthralgias, leukopenia and thrombocytopenia, spontaneous abortion and hydrops fetalis in pregnant women. Hepatitis, myocarditis, meningitis, encephalitis as well as pure red cell anemia may occur occasionally. In addition parvovirus B 19 infections have been frequently described as cause or trigger of various forms of autoimmune diseases affecting all blood cell lines, joints, connective tissue, uvea, large and small vessels. Molecular mimicry may be one major contribution to the appearance of autoimmune antibodies, fe. antiphospholipid and antineutrophil cytoplasmic antibodies as well as antinuclear antigens. These mechanisms implicated in the pathogenesis of parvovirus B 19 triggered autoimmune diseases, especially focused on the development of antiphospholipid antibodies will be discussed in this short review. (C) 2006 Elsevier B.V. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | NECROSIS-FACTOR-ALPHA; RHEUMATIC-DISEASE; 5TH DISEASE; VP1 UNIQUE; ARTHRITIS; MANIFESTATIONS; ASSOCIATION; CHILDHOOD; CHILDREN; CELLS; parvovirus B19 infection; autoimmune reaction; antiphospholipid antibodies |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 16 Dec 2020 06:41 |
| Last Modified: | 16 Dec 2020 06:41 |
| URI: | https://pred.uni-regensburg.de/id/eprint/32916 |
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