Zhang, Bo and Boettcher, Alfred and Imaizumi, Satoshi and Noda, Keita and Schmitz, Gerd and Saku, Keijiro (2007) Relation between charge-based apolipoprotein B-containing lipoprotein subfractions and remnant-like particle cholesterol levels. ATHEROSCLEROSIS, 191 (1). pp. 153-161. ISSN 0021-9150,
Full text not available from this repository. (Request a copy)Abstract
Objective: Both mildly modified LDL subfraction that carries a more-negative electric charge and remnant-like particles (RLP) are closely related to triglyceride (TG) levels. We examined the relation between the RLP-cholesterol (C) level and charge-based apolipoprotein (apo) B-containing lipoprotein subtractions as determined by capillary isotachophoresis (cITP) in patients with hypercholesterolemia. Methods and results: cITP apo B lipoprotein subtractions were identified by analyzing plasma depleted of the related lipoproteins. While fast-migrating triglyceride-rich lipoprotein (fTRL) subfraction contained both chylomicrons and VLDL fraction, slow TRL (sTRL) only contained VLDL. cITP fLDL also contained VLDL fraction, i.e., P-VLDL. Levels of cITP fTRL and sTRL were significantly correlated with serum levels of TG, RLP-C, apo C-II, and C-III. Levels of cITP sTRL were also correlated with apo E. Levels of cITP fLDL were positively correlated with not only LDL-C levels but also levels of TG, RLP-C, apo C-II, C-III, and E. Conclusion: cITP fast LDL correlated with RLP-C levels and modified the relation between RLP-C and TG levels. (c) 2006 Elsevier Ireland Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | LOW-DENSITY-LIPOPROTEIN; ANALYTICAL CAPILLARY ISOTACHOPHORESIS; HUMAN PLASMA-LIPOPROTEINS; HUMAN BLOOD-PLASMA; ELECTRONEGATIVE LDL; TRIGLYCERIDE-RICH; III HYPERLIPOPROTEINEMIA; INSULIN-RESISTANCE; ENDOTHELIAL-CELLS; RLP-CHOLESTEROL; capillary isotachophoresis; apolipoprotein B-containing lipoprotein subfractions; remnant-like particle cholesterol; apolipoprotein |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 21 Dec 2020 08:07 |
| Last Modified: | 21 Dec 2020 08:07 |
| URI: | https://pred.uni-regensburg.de/id/eprint/33053 |
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