Yoon, Mina and Borrmann, Peter and Tomanek, David (2007) Targeted medication delivery using magnetic nanostructures. JOURNAL OF PHYSICS-CONDENSED MATTER, 19 (8): 086210. ISSN 0953-8984,
Full text not available from this repository.Abstract
We use quaternion molecular dynamics simulations to describe field-induced structural transitions in systems of few magnetic dipoles and their use for targeted medication delivery. Compact ring isomers of magnetic particles are contained, together with molecules of an active medication, inside inert microcapsules. The filled microcapsules may be transported within the body using a weak, inhomogeneous magnetic field. Medication release is triggered by puncturing the container during a structural transition within the magnetic subsystem, induced by an externally applied strong magnetic field. Our simulations describe not only the time evolution of the magnetic subsystem during a successful medication release, but also address ways to suppress an accidental release induced by thermal and magnetic fluctuations.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | DIPOLAR HARD-SPHERES; ELECTRORHEOLOGICAL FLUIDS; FERROFLUIDS; ORDER; CLUSTERS; DYNAMICS; |
| Subjects: | 500 Science > 530 Physics |
| Divisions: | Physics > Institute of Theroretical Physics |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 22 Dec 2020 07:55 |
| Last Modified: | 22 Dec 2020 07:55 |
| URI: | https://pred.uni-regensburg.de/id/eprint/33167 |
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