Ott, Claudia and Heinmoeller, Ernst and Gaumann, Andreas and Schoelmerich, Juergen and Klebl, Frank (2007) Intraepithelial neoplasms (PanIN) and intraductal papillary-mucinous neoplasms (IPMN) of the pancreas as precursor lesions of pancreatic carcinoma. MEDIZINISCHE KLINIK, 102 (2). pp. 127-135. ISSN 0723-5003
Full text not available from this repository. (Request a copy)Abstract
Due to the fatal prognosis of pancreatic carcinoma, great efforts have been made to investigate precursor lesions of invasive neoplasia during the last few years. Pancreatic intraepithelial neoplasias (PanIN) have been recognized as precursor lesions of ductal adenocarcinoma, and are classified into different grades from PanIN-1A, -1B, -2, to -3. Molecular analyses have helped to define a progression model for pancreatic neoplasia. The most important step seems to be the occurrence of a PanIN-3 lesion defining a high risk of malignant transformation.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | K-RAS MUTATIONS; CYCLOOXYGENASE-2 EXPRESSION; DUCTAL ADENOCARCINOMA; CYSTIC NEOPLASMS; CANCER; TUMORS; PROGRESSION; CLASSIFICATION; RECURRENCE; DIAGNOSIS; pancreatic intraepithelial neoplasia; intraductal papillary mucinous neoplasia; precursor lesion; pancreatic carcinoma |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I Medicine > Lehrstuhl für Pathologie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 28 Oct 2020 07:50 |
| Last Modified: | 28 Oct 2020 07:50 |
| URI: | https://pred.uni-regensburg.de/id/eprint/33183 |
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