Schaefer, Fritz K. W. and Schaefer, Philipp J. and Altjohann, Christian and Bourne, Michael and DeCobelli, Francesco and Goyen, Mathias and Griffiths, Paul D. and Kopka, Lars and Kreitner, Karl F. and Link, Johann and Oberholzer, Katja and Pering, Christiane and Poeckler-Schoeninger, Christiane and Ruehm, Stefan G. and Sachoran, Mansur R. and Schulte-Altedorneburg, Gernot and Springer, Oliver S. and Steiner, Paul and Wall, Alexander and Winterer, Jan and Tombach, Bernd (2007) A multicenter, site-independent, blinded study to compare the diagnostic accuracy of contrast-enhanced magnetic resonance angiography using 1.0 M gadobutrol (Gadovist (TM)) to intraarterial digital subtraction angiography in body arteries. EUROPEAN JOURNAL OF RADIOLOGY, 61 (2). pp. 315-323. ISSN 0720-048X, 1872-7727
Full text not available from this repository. (Request a copy)Abstract
Purpose: Prospective evaluation of diagnostic accuracy of single field-of-view contrast-enhanced MR Angiography (ceMRA) with 1.0M gadobutrol compared to intraarterial DSA in body arteries. Materials and methods: In an European multicenter study 179 patients underwent ceMRA and DSA. For each indication five prospectively defined vessel segments were evaluated by local investigators onsite and by three site-independent blinded readers (BR) independently. Results: The agreement between ceMRA and DSA diagnosis was statistically significant in the onsite (96.6%) and blinded reader (86.6-90.2%) evaluation. Sensitivity, specificity, accuracy, positive (PPV) and negative predictive values (NPV) for detection of relevant stenosis (> 50%) were calculated for the right and left internal carotid arteries, and common and external iliac arteries: Sensitivity was 95-98% (onsite) and 76-96% (BR), specificity 94-96% (onsite) and 86-94% (BR), accuracy 96% (onsite) and 87-93% (BR), NPV 98-99% (onsite) and 84-98% (BR), and PPV 79-93% (onsite) and 44-91 % (BR), respectively. Conclusion: CeMRA of body arteries using 1.0 M gadobutrol provides diagnostic information comparable to intraarterial DSA. (c) 2006 Elsevier Ireland Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ACCESSORY RENAL-ARTERIES; LOWER-EXTREMITY ARTERIES; BREATH-HOLD; GADOPENTETATE DIMEGLUMINE; CONVENTIONAL ANGIOGRAPHY; CAROTID-ENDARTERECTOMY; PRELIMINARY EXPERIENCE; OCCLUSIVE DISEASE; STENOSIS; OPTIMIZATION; contrast media; magnetic resonance angiography; multicenter study |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 22 Dec 2020 11:40 |
| Last Modified: | 22 Dec 2020 11:40 |
| URI: | https://pred.uni-regensburg.de/id/eprint/33213 |
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