Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: An international consensus

Braathen, Lasse R. and Szeimies, Rolf-Markus and Basset-Seguin, Nicole and Bissonnette, Robert and Foley, Peter and Pariser, David and Roelandts, Rik and Wennberg, Ann-Marie and Morton, Colin A. (2007) Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: An international consensus. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 56 (1). pp. 125-143. ISSN 0190-9622,

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Abstract

Topical photodynamic therapy (PDT) is used to treat nonmelanoma skin cancers, such as actinic keratoses, Bowen's disease, and basal cell carcinoma (superficial and nodular). This article presents up-to-date, practical, evidence-based recommendations on the use of topical PDT using 5-aminolevulinic acid or methyl aminolevulinate for the treatment (and prevention) of nonmelanoma skin cancers. A systematic literature review was conducted (using MEDLINE), and recommendations were made on the basis of the quality of evidence for efficacy, safety/tolerability, cosmetic outcome., and patient satisfaction/preference. Topical PDT is highly effective in the treatment of actinic keratoses, Bowen's disease, superficial and thin nodular basal cell carcinomas, with cosmesis typically superior to to that achieved with existing standard therapies. PDT may also be a means of preventing certain nonmelanoma skin cancers in immunosuppressed patients.

Item Type: Article
Uncontrolled Keywords: BASAL-CELL CARCINOMA; DELTA-AMINOLEVULINIC-ACID; TOPICAL METHYL AMINOLEVULINATE; RENAL-TRANSPLANT RECIPIENTS; BOWENS-DISEASE; ACTINIC KERATOSES; 5-AMINOLEVULINIC ACID; FOLLOW-UP; ENDOGENOUS PROTOPORPHYRIN; RANDOMIZED MULTICENTER;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Dermatologie und Venerologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 13 Jan 2021 09:11
Last Modified: 13 Jan 2021 09:11
URI: https://pred.uni-regensburg.de/id/eprint/33465

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