Renal cell carcinoma metastases to the thyroid gland - 8 cases reported

Iesalnieks, Igors and Trupka, Arnold and Raab, Maximilian and Glockzin, Gabriel and Woenckhaus, Matthias and Schlitt, Hans Juergen and Agha, Ayman (2007) Renal cell carcinoma metastases to the thyroid gland - 8 cases reported. THYROID, 17 (1). pp. 49-52. ISSN 1050-7256,

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Abstract

Objective: Clinically important, isolated metastases to the thyroid gland is a rare occurrence. Renal cell carcinoma (RCC) is the most common primary tumor site. We report on 8 cases of late onset metachronous thyroid metastases of RCC. Design: Eight patients presented with metachronous thyroid metastases at a median of 12 years (range 9-18 years) after nephrectomy for RCC. Two patients had simultaneous lung and lymph node metastases, respectively. Four patients had been previously operated for other metastases I to 5 years earlier, three of them due to pancreatic metastases. The leading symptom was neck enlargement in all but one case. Main outcome: Four total thyroidectomies, 3 subtotal resections, and 1 lobectomy were performed. Complete removal of metastases were achieved in all but one case. There was no postoperative morbidity. Six metastases were bilateral, two unilateral. The 4 year overall survival rate following metastasectomy was 53%, median survival from the date of nephrectomy was 21 years. Conclusion: Long-term survival can be achieved after resection of isolated metachronous RCC metastases to the thyroid gland. Total thyroidectomy is not required, unless it is necessary for complete metastasectomy.

Item Type: Article
Uncontrolled Keywords: PANCREATIC RESECTION; SURGICAL-TREATMENT; CLINICAL-TRIALS; DISEASE; NEPHRECTOMY; TUMORS; renal cell carcinoma; thyroid metastases
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Chirurgie
Medicine > Lehrstuhl für Pathologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 15 Jan 2021 06:06
Last Modified: 15 Jan 2021 06:06
URI: https://pred.uni-regensburg.de/id/eprint/33612

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