Budweiser, Stephan and Moertl, Markus and Joerres, Rudolf A. and Windisch, Wolfram and Heinemann, Frank and Pfeifer, Michael (2006) Respiratory muscle training in restrictive thoracic disease: A randomized controlled trial. ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, 87 (12). pp. 1559-1565. ISSN 0003-9993, 1532-821X
Full text not available from this repository. (Request a copy)Abstract
Objective: To investigate the effects of respiratory muscle training (PMT) in patients with restrictive thoracic disorders and intermittent noninvasive positive-pressure ventilation (NPPV). Design: Prospective randomized controlled trial. Setting: Home-based RMT, with assessment in a primary care pulmonary center. Participants: Thirty patients with restrictive thoracic disorders; 28 patients completed the trial. Intervention: Three months of RMT by isocapnic hyperpnea or sham training. Main Outcome Measures: Respiratory muscle strength and endurance, lung function, exercise performance, and health-related quality of life (HRQOL). Results: After RMT, maximal inspiratory mouth pressure was increased (27.6% +/- 36.5%, P=.013). In patients who could perform cycle ergometer testing (n= 17), peak oxygen consumption (2.24 +/- 3.39mL.kg(-1).min- vs -1.71 +/- 2.54mL.kg(-1).min(-1), P=.014) and maximal work rate (9.4 +/- 14.8W vs -5.1 +/- 10.8W, P=.043) increased relative to a control group. Similar differences occurred regarding changes of HRQOL (physical performance, 3.3 +/- 11.4 score vs -6.6 +/- 9.0 score; P=.012) and time of ventilator use (-0.6 +/- 1.2h/d vs 0.4 +/- 0.5h/d, P=.010). Lung volumes, 12-second maximum voluntary ventilation, 6-minute walking distance, and blood gases were unchanged. Conclusions: In patients with restrictive thoracic disorders and NPPV, RMT improved inspiratory muscle strength. Exercise performance and HRQOL were improved when the 2 groups were compared. RMT was practicable and safe despite severe respiratory impairment. Further evaluation, including different training intensities and modalities, seems warranted.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | OBSTRUCTIVE PULMONARY-DISEASE; POSITIVE PRESSURE VENTILATION; QUALITY-OF-LIFE; NONINVASIVE VENTILATION; NEUROMUSCULAR DISORDERS; MECHANICAL VENTILATION; EXERCISE CAPACITY; ENDURANCE; FAILURE; REHABILITATION; breathing exercises; chest; rehabilitation; respiratory muscle training; scoliosis; ventilation |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin II |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 15 Jan 2021 13:10 |
| Last Modified: | 15 Jan 2021 13:10 |
| URI: | https://pred.uni-regensburg.de/id/eprint/33668 |
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