Drug evaluation: OGX-011, a clusterin-inhibiting antisense oligonucleotide

Schmitz, Gerd (2006) Drug evaluation: OGX-011, a clusterin-inhibiting antisense oligonucleotide. CURRENT OPINION IN MOLECULAR THERAPEUTICS, 8 (6). pp. 547-554. ISSN 1464-8431,

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Abstract

OncoGenex Technologies Inc in collaboration with Isis Pharmaceuticals Inc is developing OGX-011, an intravenously administered clusterin-inhibiting antisense oligonucleotide, to potentially sensitize solid tumors that are resistant to conventional cancer therapeutics. Phase II clinical trials of OGX-011 in combination with chemotherapeutic drugs are underway in NSCLC, prostate and breast cancer.

Item Type: Article
Uncontrolled Keywords: PROSTATE-CANCER; IN-VITRO; GENE; CELLS; VIVO; PROGRESSION; CHAPERONE; THERAPY;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Depositing User: Dr. Gernot Deinzer
Date Deposited: 15 Jan 2021 13:17
Last Modified: 15 Jan 2021 13:17
URI: https://pred.uni-regensburg.de/id/eprint/33680

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