Classen, Carl Friedrich and Warmuth-Metz, M. and Papke, K. and Trotter, A. and Wolff, J. E. A. and Wagner, S. (2006) Late response to radiochemotherapy in pediatric glioblastoma: Report on two patients treated according to HIT-GBM protocols. PEDIATRIC HEMATOLOGY AND ONCOLOGY, 23 (8). pp. 631-637. ISSN 0888-0018,
Full text not available from this repository. (Request a copy)Abstract
High-grade gliomas in children are rare and the best treatment is undetermined. The German language group study HIT-GBM compares various induction protocols for subsequent patient cohorts. Currently, cisplatinum, etoposide, ifosfamide, and vincristine are given simultaneously with extended-field radiotherapy. Imaging is done 3 weeks after to define treatment response, followed by 6-weekly controls during consolidation with lomustine, vincristine, and prednisone. The authors report on 2 patients with incompletely resected glioblastoma multiforme in which response was lacking 3 weeks after radiochemotherapy but became evident 12 weeks later. This suggests that later time points are required to assess induction protocol response.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MULTIFORME; GLIOMA; glioblastoma; response control; radiochemotherapy; pediatric |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Abteilung für Pädiatrische Hämatologie, Onkologie und Stammzelltransplantation |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 18 Jan 2021 09:40 |
| Last Modified: | 18 Jan 2021 09:40 |
| URI: | https://pred.uni-regensburg.de/id/eprint/33720 |
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