Bein, Th. and Obed, A. and Schlitt, H. J. (2006) Protection of multiorgan failure in an organ donor: timely identification and protective therapy in a patient after multitrauma. DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 131 (44). pp. 2465-2468. ISSN 0012-0472,
Full text not available from this repository. (Request a copy)Abstract
Anamnesis: A 18-year-old woman suffered from severe multi-trauma in combination with acute brain injury (Glasgow Coma Scale Score = 4) after road accident. After prolonged rescue measures and emergency stabilisation the patient was transferred by helicopter to the emergency department of our clinic. Investigations: Cranial computertomography showed a severe general cerebral edema and a marked reduction in cerebral perfusion. Additionally, blunt abdominal injury, severe chest injury and multiple fractures were seen. Due to the severe and diffuse brain injury, a neurosurgical intervention was not possible. The patient was transferred to the intensive care unit. Therapy and course: Intensive supportive therapy was started (artificial ventilation, massive transfusion, volume replacement, insertion of a chest tube, renal replacement therapy). Control cerebral computertomography indicated a complete destruction of the cerebral parenchyma and infarction. Sedation was stopped. After 48-hours of intensive care therapy brain death was stated and the approval for organ donation was given by the next of kin. Heart and kidneys were explanted and transplanted successfully. Conclusion: Even under conditions of limited organ functions early identification and maximal supportive therapy may help to supply organ donation. Under certain condition, multiorgan failure may be reversible in possible organ donors.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ; organ donation; multiorgan failure; intensive care therapy; organ protection |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie Medicine > Lehrstuhl für Orthopädie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 18 Jan 2021 09:57 |
| Last Modified: | 18 Jan 2021 09:57 |
| URI: | https://pred.uni-regensburg.de/id/eprint/33783 |
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