Diagnosis and therapy of auditory synaptopathy/neuropathy

Moser, T. and Strenzke, N. and Meyer, A. and Lesinski-Schiedat, A. and Lenarz, T. and Beutner, D. and Foerst, A. and Lang-Roth, R. and von Wedel, H. and Walger, M. and Gross, M. and Keilmann, A. and Limberger, A. and Steffens, T. and Strutz, J. (2006) Diagnosis and therapy of auditory synaptopathy/neuropathy. HNO, 54 (11). pp. 833-839. ISSN 0017-6192, 1433-0458

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Abstract

Pathological auditory brainstem responses (lack of responses, elevated thresholds and perturbed waveforms) in combination with present otoacoustic emissions are typical audiometric findings in patients with a hearing impairment that particularly affects speech comprehension or complete deafness. This heterogenous group of disorders first described as "auditory neuropathy" includes dysfunction of peripheral synaptic coding of sound by inner hair cells (synaptopathy) and/or of the generation and propagation of action potentials in the auditory nerve (neuropathy). This joint statement provides prevailing background information as well as recommendations on diagnosis and treatment. The statement focuses on the handling in the german language area but also refers to current international statements.

Item Type: Article
Uncontrolled Keywords: INNER HAIR-CELLS; HEARING-LOSS; COCHLEAR IMPLANTATION; ENCODING OTOFERLIN; OTOF GENE; NEUROPATHY; DEAFNESS; MUTATIONS; CHILDREN; INFANTS; synaptopathy; neuropathy; deafness; speech recognition
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde
Depositing User: Dr. Gernot Deinzer
Date Deposited: 19 Jan 2021 11:17
Last Modified: 19 Jan 2021 11:17
URI: https://pred.uni-regensburg.de/id/eprint/33804

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