Suhs, T. and Koenig, Burkhard (2006) Synthesis of guanidines in solution. MINI-REVIEWS IN ORGANIC CHEMISTRY, 3 (4). pp. 315-331. ISSN 1570-193X, 1875-6298
Full text not available from this repository. (Request a copy)Abstract
The guanidinium group is a typical functional group in molecules with physiological or biological activity. Its geometry and physiochemical properties are of importance for molecular recognition processes. We discuss in this review modern synthetic methods for the introduction of the guanidinium group and focus our survey on examples from natural product synthesis and drug synthesis. The presented methods are sufficiently mild and selective to allow guanidylation of more complex structures.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SOLID-PHASE SYNTHESIS; POTENTIAL CHIRAL SUPERBASES; AMINO-ACIDS; INFLUENZA NEURAMINIDASE; ANTIFUNGAL RESISTANCE; PROTECTED GUANIDINES; PROTEASE INHIBITORS; RNA RECOGNITION; ACTIVE-SITE; SIDE-CHAINS; guanidinium; urea; thiourea; guanidinylation reagents; natural products; drug synthesis |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 20 Jan 2021 07:03 |
| Last Modified: | 20 Jan 2021 07:03 |
| URI: | https://pred.uni-regensburg.de/id/eprint/33825 |
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