Impact of radiotherapy on implant-based prosthetic rehabilitation in patients with head and neck cancer: A prospective observational study on implant survival and quality of life-Preliminary results

Ettl, Tobias and Weindler, Janet and Gosau, Martin and Mueller, Steffen and Hautmann, Matthias and Zeman, Florian and Koller, Michael and Papavasileiou, Dimitrios and Buergers, Ralf and Driemel, Oliver and Schneider, Isabel and Klingelhoeffer, Christoph and Meier, Johannes and Wahlmann, Ulrich and Reichert, Torsten E. (2016) Impact of radiotherapy on implant-based prosthetic rehabilitation in patients with head and neck cancer: A prospective observational study on implant survival and quality of life-Preliminary results. JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY, 44 (9). pp. 1453-1462. ISSN 1010-5182, 1878-4119

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Abstract

Purpose: To study implant-based prosthetic rehabilitation of head and neck cancer patients with focus on implant survival and quality of life. Materials and methods: The prospective observational study presents preliminary results of 29 edentulous head neck cancer patients (20 patients after radiotherapy) with 165 OsseoSpeed implants. Implant success after 1-year follow-up was evaluated by means of the Albrektsson criteria. Quality of life was analysed with the EORTC QLQ-C30, QLQ-H&N35, and OHIP 14 questionnaires. Results: The overall implant survival rate after 1 year was 95.2% (157/165). Implant success measured by the Albrektsson criteria showed a lower success rate of 86.7% (143/165), mainly because of peri-implant marginal bone loss with a mean of 0.8 mm after 1 year. Xerostomia (p = 0.008), implant insertion within the radiation target volume (p = 0.09), implantation in transplanted bone (p = 0.05), and smoking (p = 0.041) were the main reasons for implant failure, followed by D4 bone quality, maxillary implant site, and insufficient primary stability. Speaking, swallowing, eating, as well as social integration and individual self-confidence had considerably improved 1 year after denture placement compared to before treatment. Conclusion: Implant-based prosthetic rehabilitation of head and neck cancer patients is possible at a calculable risk and significantly improves patients' quality of life. (C) 2016 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

Item Type: Article
Uncontrolled Keywords: FOLLOW-UP PERIOD; ORAL-CANCER; OF-LIFE; DENTAL IMPLANTS; IRRADIATED PATIENTS; CLINICAL-EVALUATION; ENDOSTEAL IMPLANTS; HEALTH; THERAPY; SURGERY; Head and neck cancer; Radiotherapy; Prosthetic rehabilitation; Implant success; Quality of life
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Mund-, Kiefer- und Gesichtschirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 04 Apr 2019 11:55
Last Modified: 04 Apr 2019 11:55
URI: https://pred.uni-regensburg.de/id/eprint/3390

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