Correlation between optical coherence tomography and autofluorescence in acute posterior multifocal placoid pigment epitheliopathy

Souka, Ahmed A. R. and Hillenkamp, Jost and Gora, Felix and Gabel, Veit-Peter and Framme, Carsten (2006) Correlation between optical coherence tomography and autofluorescence in acute posterior multifocal placoid pigment epitheliopathy. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 244 (10). pp. 1219-1223. ISSN 0721-832X,

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Abstract

Purpose: To report a case of bilateral acute posterior multifocal placoid pigment epitheliopathy (APMPPE) evaluated by optical coherence tomography (OCT), fundus autofluorescence (AF) and microperimetry, both in the acute phase and after resolution of symptoms. Methods: Complete ophthalmological evaluation, including fluorescein angiography, OCT, AF, and microperimetry upon presentation and 1 month later, after lesions have subsided. An attempt to correlate the findings on presentation and changes after resolution is performed using the results of these new investigational techniques. Results APMPPE showed hyperreflectance in OCT at the level of the outer retinal layers, without increase in retinal thickness. AF revealed early decreased fluorescence due to a masking effect, and later reveals increased fluorescence after resolution of OCT findings. Function is disturbed at the lesion sites, as shown by microperimetry, and later returns to near normal values on microperimetry. Conclusion APMPPE shows outer retinal layers changes on OCT, which resolve totally after subsidence of the acute phase. AF shows areas of increased fluorescence after resolution, with near normal return of function on microperimetry.

Item Type: Article
Uncontrolled Keywords: PERFUSION; DISEASES; acute posterior multifocal placoid pigment epitheliopathy; autofluorescence; microperimetry; optical coherence tomography; retinal pigment epithelium
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Augenheilkunde
Depositing User: Dr. Gernot Deinzer
Date Deposited: 25 Jan 2021 08:01
Last Modified: 25 Jan 2021 08:01
URI: https://pred.uni-regensburg.de/id/eprint/33925

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