Perylene-3,4 : 9,10-tetracarboxylic acid bisimide dye as an artificial DNA base surrogate

Wagner, Clemens and Wagenknecht, Hans-Achim (2006) Perylene-3,4 : 9,10-tetracarboxylic acid bisimide dye as an artificial DNA base surrogate. ORGANIC LETTERS, 8 (19). pp. 4191-4194. ISSN 1523-7060,

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Abstract

A phosphoramidite of the perylene bisimide dye was synthesized as a DNA building block that allows incorporation of this chromophore as an artificial nucleoside surrogate either at the 5'-terminus or at internal positions of duplex DNA. The internally incorporated perylene bisimide chromophore shows strong interactions with the DNA base stack; the 5'-terminally attached perylene bisimide is able to induce dimerization of two whole DNA duplexes.

Item Type: Article
Uncontrolled Keywords: PERYLENE DYES; CHARGE DONOR; PHENANTHRIDINIUM; FLUORESCENT; DERIVATIVES; NUCLEOSIDE; DUPLEX; IMIDE;
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Alumni or Retired Professors > Arbeitskreis Prof. Dr. Hans-Achim Wagenknecht
Depositing User: Dr. Gernot Deinzer
Date Deposited: 01 Feb 2021 07:55
Last Modified: 01 Feb 2021 07:56
URI: https://pred.uni-regensburg.de/id/eprint/34026

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