Dietl, Barbara and Marienhagen, Jorg and Kuehnel, Thomas and Schaefer, Christof and Koelbl, Oliver (2006) FDG-PET in radiotherapy treatment planning of advanced head and neck cancer - A prospective clinical analysis. AURIS NASUS LARYNX, 33 (3). pp. 303-309. ISSN 0385-8146,
Full text not available from this repository. (Request a copy)Abstract
Background: A prospective clinical analysis was carried out to assess the diagnostic and therapeutic impact of fluorodeoxyglucose positron emission tomography (FDG-PET) on planning radiotherapy in patients with advanced head and neck cancer in AJCC Stages III/IV. Methods: From July 1999 to May 2004 FDG-PET was performed in 49 patients prior to radiotherapy for exclusion of systemic disease, synchronous second or unknown primary tumors. Results: 45/49 (91.9%) FDG-PET findings could be confirmed in comparison with conventional imaging and the clinical follow up of 9.5 months. 21/49 FDG-PET (42.8%) yielded new diagnostic information with therapeutic implications in 20/49 (40.8%) cases. The therapy strategy was changed in 14/49 patients, minor modifications in the portal design occurred in 6/49 patients. 9/49 (18.3%) FDG-PET supported a curative strategy, 11/49 (22.4%) a palliative one. Conclusions: FDG-PET is a useful and important diagnostic tool mainly for exclusion of systemic disease in advanced head and neck cancer, thus influencing radiotherapy in 20/49 (40.8%) of patients investigated in our study. (C) 2006 Elsevier Ireland Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SQUAMOUS-CELL CARCINOMA; POSITRON-EMISSION-TOMOGRAPHY; LYMPH-NODE METASTASES; DISTANT METASTASES; PRIMARY TUMOR; RADIATION-THERAPY; UNKNOWN PRIMARY; CHEMOTHERAPY; STATISTICS; EXTENSION; FDG-PET; diagnostic impact; therapeutic impact; head and neck cancer; radiotherapy treatment planning |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde Medicine > Lehrstuhl für Strahlentherapie Medicine > Abteilung für Nuklearmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 01 Feb 2021 10:26 |
| Last Modified: | 01 Feb 2021 10:26 |
| URI: | https://pred.uni-regensburg.de/id/eprint/34051 |
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