Steinbrecher, Andreas and Berlit, Peter (2006) Intravenous immunoglobulin treatment in vasculitis and connective tissue disorders. JOURNAL OF NEUROLOGY, 253. pp. 39-49. ISSN 0340-5354
Full text not available from this repository. (Request a copy)Abstract
Vasculitis syndromes and connective tissue disorders are heterogeneous and mostly rare multisystem disorders with various autoimmune mechanisms driving tissue inflammation and remodeling, ischemic and hemorrhagic tissue damage. While the nervous system can be affected by most of these diseases, the pathogenesis for neural involvement is often ambiguous and elusive for the clinician. Intravenous immunoglobulins (IVIG) have been used for the treatment of most of these disorders. However, a thorough review of the literature indicates that the role for IVIG has to be discussed for individual entities, has often only anecdotal evidence, and is particularly hard to define with respect to neurological manifestations. This review gathers the available evidence on the efficacy of IVIG in neurologically relevant rheumatic diseases, leading to recommendations for their clinical use.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SYSTEMIC-LUPUS-ERYTHEMATOSUS; CENTRAL-NERVOUS-SYSTEM; CATASTROPHIC ANTIPHOSPHOLIPID SYNDROME; REFRACTORY RHEUMATOID-ARTHRITIS; CUTANEOUS POLYARTERITIS-NODOSA; HENOCH-SCHONLEIN PURPURA; GAMMA-GLOBULIN TREATMENT; KAWASAKI-DISEASE; SJOGRENS-SYNDROME; LIVEDOID VASCULITIS; vasculitis; lupus erythematosus; rheumatic diseases; intravenous immunoglobulin |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurologie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 24 Feb 2021 07:46 |
| Last Modified: | 24 Feb 2021 07:46 |
| URI: | https://pred.uni-regensburg.de/id/eprint/34111 |
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