Wanninger, Claudia and Wagenknecht, Hans-Achim (2006) Indole as an artificial DNA base incorporated via an acyclic 2 '-deoxyriboside substitute. SYNLETT (13). pp. 2051-2054. ISSN 0936-5214, 1437-2096
Full text not available from this repository. (Request a copy)Abstract
Indole was synthetically incorporated into DNA as an artificial base at specific sites of duplex DNA. An acyclic substitute for the 2'-deoxyribose was applied in order to obtain a chemically stable nucleoside analogue that can be synthesized by a fast and facile procedure. Studies by methods of optical spectroscopy revealed that the indole base surrogate is intercalated into the DNA base stack and behaves as a universal base analogue with only little influence of the counterbase.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ELECTRON-TRANSFER; CHARGE-TRANSPORT; PHENANTHRIDINIUM; NUCLEOSIDES; FLUORIDE; ANALOGS; dNA; indole; oligonucleotide; base analogue |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie > Alumni or Retired Professors > Arbeitskreis Prof. Dr. Hans-Achim Wagenknecht |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 03 Feb 2021 10:59 |
| Last Modified: | 03 Feb 2021 10:59 |
| URI: | https://pred.uni-regensburg.de/id/eprint/34162 |
Actions (login required)
 |
View Item |
