Schuele, R. and Holland-Letz, T. and Klimpe, S. and Kassubek, J. and Klopstock, T. and Mall, V. and Otto, S. and Winner, B. and Schoels, L. (2006) The Spastic Paraplegia Rating Scale (SPRS) - A reliable and valid measure of disease severity. NEUROLOGY, 67 (3). pp. 430-434. ISSN 0028-3878,
Full text not available from this repository. (Request a copy)Abstract
Objective: To develop and evaluate a clinical Spastic Paraplegia Rating Scale ( SPRS) to measure disease severity and progression. Methods: A 13-item scale was designed to rate functional impairment occurring in pure forms of spastic paraplegia (SP). Additional symptoms constituting a complicated form of SP are recorded in an inventory. Two independent patient cohorts were evaluated in a two-step validation procedure. Results: Application of SPRS requires less than 15 minutes and does not require any special equipment, so it is suitable for an outpatient setting. Interrater agreement of SPRS was high (intraclass correlation coefficient = 0.99). Reliability was further supported by high internal consistency ( Cronbach alpha = 0.91). SPRS values were almost normally distributed without apparent floor or ceiling effect. Construct validity was shown by high correlation of SPRS to Barthel Index and the International Cooperative Ataxia Rating Scale ( convergent validity) and low correlation to Mini-Mental Status Examination ( discriminant validity). Conclusion: The Spastic Paraplegia Rating Scale is a reliable and valid measure of disease severity.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | INTERRATER RELIABILITY; HEREDITARY; ATAXIA; ICARS; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 08 Feb 2021 07:36 |
| Last Modified: | 08 Feb 2021 07:36 |
| URI: | https://pred.uni-regensburg.de/id/eprint/34174 |
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