Fraile, Jose M. and Perez, Lgnacio and Mayoral, Jose A. and Reiser, Oliver (2006) Multipurpose box- and azabox-based immobilized chiral catalysts. ADVANCED SYNTHESIS & CATALYSIS, 348 (12-13). pp. 1680-1688. ISSN 1615-4150,
Full text not available from this repository. (Request a copy)Abstract
Azabis(oxazolines) can be used as chiral ligands in the copper-catalyzed enantioselective Mukaiyama aldol reaction. When supported on solids, azabis(oxazoline)-copper complexes are more easily deactivated than their analogous bis(oxazoline)copper complexes, and are not compatible with the use of coordinating solvents in the method of preparation. The performance of the immobilized catalysts (up to 86 % ee) depends on the support and the reaction solvent, with some positive effect on enantioselectivity due to surface effects. The deactivation is not irreversible and the deactivated catalysts show excellent performance in the cyclopropanation reaction, providing added value to the supported multipurpose catalysts.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ENANTIOSELECTIVE ALDOL ADDITIONS; SUPPORTED BIS(OXAZOLINE)-COPPER COMPLEXES; C(2)-SYMMETRIC COPPER(II) COMPLEXES; POLYMER-BOUND BIS(OXAZOLINE); OXAZOLINE-CONTAINING LIGANDS; DIELS-ALDER REACTIONS; CYCLOPROPANATION REACTIONS; ASYMMETRIC HYDROGENATION; ELECTROSTATIC INTERACTIONS; LEWIS-ACIDS; asymmetric catalysis; azabis(oxazolines); cyclopropanation; Mukaiyama aldol; supported catalysts |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 08 Feb 2021 08:08 |
| Last Modified: | 08 Feb 2021 08:08 |
| URI: | https://pred.uni-regensburg.de/id/eprint/34181 |
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