Mathes, J. and Burger, M. and Gschwend, J. E. and Hakenberg, O. W. and Krege, S. and Lehmann, J. and Miller, K. and Roigas, J. and Roth, S. and Kaelble, T. (2016) Effects of modified inclusion criteria and negative reporting about PSA screening on the number of potentially recruitable patients for the PREFERE study. UROLOGE, 55 (9). pp. 1213-1217. ISSN 0340-2592, 1433-0563
Full text not available from this repository. (Request a copy)Abstract
The PREFERE study is currently below expectations. The objective of this study was to investigate the effect of the modification of the inclusion criteria in 2015 on the number of recruitable patients with localized prostate cancer. Furthermore we analyzed whether fewer cases of low-risk prostate cancer were detected in 2014 than in 2010. Prostate biopsies of 2136 patients (9 hospitals) of the years 2010 and 2014 were retrospectively reviewed, regarding the eligibility for participation in the PREFERE study. According to PREFERE criteria version 3.2, 16.8 % (in 2010) and 16.7 % (in 2014) of the patients fulfilled the inclusion criteria for the study, whereas 41.9 % (in 2010) and 30.1 % (in 2014) of the patients met the criteria in version 5.0. Our results indicate that the modified inclusion criteria result in an increase in the number of recruitable patients for the PREFERE study. Furthermore, there were 11.8 % fewer cases of potentially recruitable patients in 2014 than in 2010 by use of version 5.0. This is a possible indication for an altered use of prostate biopsy.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | LOCALIZED PROSTATE-CANCER; RADICAL PROSTATECTOMY; RANDOMIZED-TRIAL; RADIOTHERAPY; MORTALITY; OUTCOMES; PREFERE study; Inclusion criteria; Prostate biopsy; Low-risk prostate cancer |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Urologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 04 Apr 2019 13:22 |
| Last Modified: | 04 Apr 2019 13:22 |
| URI: | https://pred.uni-regensburg.de/id/eprint/3425 |
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