Klebl, F. and Endlicher, E. and Kullmann, F. (2006) Palliative therapy in cholangio- and gallbladder carcinoma. ZEITSCHRIFT FUR GASTROENTEROLOGIE, 44 (7). pp. 587-598. ISSN 0044-2771, 1439-7803
Full text not available from this repository. (Request a copy)Abstract
Non-resectable cholangiocarcinoma and gallbladder carcinoma have a poor prognosis. In addition to the general aspects of "best supportive care", biliary drainage is an important part of the palliative treatment of patients with malignant biliary stenosis. Photodynamic therapy has led to an improved median survival in hilar cholangiocarcinoma in two controlled studies. The survival benefit of external radiation or intraluminal brachytherapy has not yet been convincingly demonstrated. Whether or not systemic chemotherapy should be applied is still under debate. A single study including advanced biliary and pancreatic cancer patients has demonstrated a survival benefit for the combined group. In recent years, new chemotherapy protocols have been applied, some with promising results. Intra-arterial chemotherapy and chemotherapeutically coated stents have not been evaluated well enough to be recommended outside clinical studies. Ablative therapies have been used in a limited number of patients only. Further studies are necessary to clarify whether these treatment modalities are effective.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PHASE-II TRIAL; ADVANCED BILIARY-TRACT; EXTERNAL-BEAM RADIOTHERAPY; BILE-DUCT CARCINOMA; HIGH-DOSE 5-FLUOROURACIL; NONRESECTABLE HILAR CHOLANGIOCARCINOMA; MALIGNANT GASTRODUODENAL OBSTRUCTION; SINGLE-AGENT GEMCITABINE; PHOTODYNAMIC THERAPY; MITOMYCIN-C; cholangiocellular carcinoma; gallbladder carcinoma; Klatskin's tumour; cholangiocarcinoma |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I |
| Depositing User: | Petra Gürster |
| Date Deposited: | 16 Feb 2021 08:41 |
| Last Modified: | 16 Feb 2021 08:41 |
| URI: | https://pred.uni-regensburg.de/id/eprint/34419 |
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