Langguth, Berthold and Zowe, Marc and Landgrebe, Michael and Sand, Philipp and Kleinjung, Tobias and Binder, Harald and Hajak, Gran and Eichhammer, Peter (2006) Transcranial magnetic stimulation for the treatment of tinnitus: A new coil positioning method and first results. BRAIN TOPOGRAPHY, 18 (4). pp. 241-247. ISSN 0896-0267, 1573-6792
Full text not available from this repository. (Request a copy)Abstract
Auditory phantom perceptions are associated with hyperactivity of the central auditory system. Neuronavigation guided repetitive transcranial magnetic stimulation (rTMS) of the area of increased activity was demonstrated to reduce tinnitus perception. The study aimed at developing an easy applicable standard procedure for transcranial magnetic stimulation of the primary auditory cortex and to investigate this coil positioning strategy for the treatment of chronic tinnitus in clinical practice. The left gyrus of Heschl was targeted in 25 healthy subjects using a frameless stereotactical system. Based on individual scalp coordinates of the coil, a positioning strategy with reference to the 10-20-EEG system was developed. Using this coil positioning approach we started an open treatment trial. 28 patients with chronic tinnitus received 10 sessions of rTMS (intensity 110% of motor threshold, I Hz, 2000 Stimuli/day). Being within a range of about 20 mm diameter, the scalp coordinates for stimulating the primary auditory cortex allowed to determine a standard procedure for coil positioning. Clinical validation of this coil positioning method resulted in a significant improvement of tinnitus complaints (p < 0.001). The newly developed coil positioning strategy may have the potential to offer a more easy-to-use stimulation approach for treating chronic tinnitus as compared with highly sophisticated, imaging guided treatment methods.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | RESISTANT AUDITORY HALLUCINATIONS; MOTOR CORTEX; RTMS; DEPRESSION; FREQUENCY; REORGANIZATION; SCHIZOPHRENIA; SYSTEM; BRAIN; GYRUS; coil positioning; EEG coordinates; transcranial magnetic stimulation; auditory phantom perception; chronic tinnitus; auditory hallucinations |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde Medicine > Lehrstuhl für Psychiatrie und Psychotherapie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 15 Feb 2021 06:25 |
| Last Modified: | 15 Feb 2021 06:25 |
| URI: | https://pred.uni-regensburg.de/id/eprint/34466 |
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