Gehrmann, Mathias (2006) Drug evaluation: STA-4783 - enhancing taxane efficacy by induction of Hsp70. CURRENT OPINION IN INVESTIGATIONAL DRUGS, 7 (6). pp. 574-580. ISSN 1472-4472,
Full text not available from this repository. (Request a copy)Abstract
The apoptosis stimulator STA-4783 acts by inducing expression of heat shock protein (Hsp) 70 on tumor cell surfaces and disrupting the cytoskeletal network. Currently in development by Synta Pharmaceuticals for the potential treatment of solid tumors, phase II clinical trials in non-small-cell lung cancer, melanoma and sarcoma have been initiated.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | NATURAL-KILLER-CELLS; SOLID TUMORS; HEAT-SHOCK-PROTEIN-70; TAXOL; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 15 Feb 2021 06:40 |
| Last Modified: | 15 Feb 2021 06:40 |
| URI: | https://pred.uni-regensburg.de/id/eprint/34473 |
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