Lord, Phillip and Spiering, Rachel and Aguillon, Juan C. and Anderson, Amy E. and Appel, Silke and Benitez-Ribas, Daniel and ten Brinke, Anja and Broere, Femke and Cools, Nathalie and Cuturi, Maria Cristina and Diboll, Julie and Geissler, Edward K. and Giannoukakis, Nick and Gregori, Silvia and van Ham, S. Marieke and Lattimer, Staci and Marshall, Lindsay and Harry, Rachel A. and Hutchinson, James A. and Isaacs, John D. and Joosten, Irma and van Kooten, Cees and Lopez Diaz de Cerio, Ascension and Nikolic, Tatjana and Oral, Haluk Barbaros and Sofronic-Milosavljevic, Ljiljana and Ritter, Thomas and Riquelme, Paloma and Thomson, Angus W. and Trucco, Massimo and Vives-Pi, Marta and Martinez-Caceres, Eva M. and Hilkens, Catharien M. U. (2016) Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies. PEERJ, 4: e2300. ISSN 2167-8359,
Full text not available from this repository. (Request a copy)Abstract
Cellular therapies, with tolerogenic antigen-presenting cells (tolAPC) show great promise for the treatment of autoimmune diseases and for the prevention of destructive immune responses after transplantation The methodologies for generating tolAPC vary greatly between different laboratories, making it difficult to compare data from different studies; thus constituting a major hurdle for the development of standardised tolAPC therapeutic products. Here we describe an initiative by members of the tolAPC field to generate a minimum information model for tolAPC (MITAP), providing a reporting framework that will make differences and similarities between tolAPC products transparent. In this way, MITAP constitutes a first but important step towards the production of standardised and reproducible tolAPC for clinical application.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | DENDRITIC CELLS; DISEASE; Cell therapy; Minimum information model; Antigen-presenting cells; Autoimmune disease; Transplantation; Tolerogenic dendritic cells; Regulatory macrophages; Reporting guidelines |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 05 Apr 2019 09:02 |
| Last Modified: | 05 Apr 2019 09:02 |
| URI: | https://pred.uni-regensburg.de/id/eprint/3456 |
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