Repetitive transcranial magnetic stimulation (rTMS): a new therapeutic approach in subjective tinnitus?

Londero, Alain and Langguth, Berthold and De Ridder, D. and Bonfils, P. and Lefaucheur, J-P (2006) Repetitive transcranial magnetic stimulation (rTMS): a new therapeutic approach in subjective tinnitus? NEUROPHYSIOLOGIE CLINIQUE-CLINICAL NEUROPHYSIOLOGY, 36 (3). pp. 145-155. ISSN 0987-7053,

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Abstract

Subjective (non-recordable) tinnitus is the conscious perception of a phantom sound, and a very frequent, sometimes disabling, condition. Even if subjective tinnitus is often related to peripheral hearing loss, neurophysiological and functional imaging studies provide increasing evidence for an involvement both auditory and non-auditory central nervous pathways in the generation of tinnitus and related distress. Repetitive transcranial magnetic stimulation (rTMS) has been proposed to relieve tinnitus by reducing auditory cortex hyperexcitability associated with this condition. This paper will review the first clinical results reported in auditory cortex rTMS studies, with special reference to the pathophysiology of tinnitus processing and the mechanisms of action of rTMS. Although rTMS appears to be a very promising toot for the diagnosis and the treatment of tinnitus patients, available knowledge is still very limited at the moment. Further basic research and clinical studies are needed in order to optimize the parameters of stimulation (stimulus frequency, cortical target definition) and to validate the application of this technique in the management of patients with disabling tinnitus. (c) 2006 Elsevier Masson SAS. All rights reserved.

Item Type: Article
Uncontrolled Keywords: PRIMARY AUDITORY-CORTEX; CORTICOFUGAL MODULATION; INFERIOR COLLICULUS; MOTOR CORTEX; HEARING-LOSS; INTRACTABLE TINNITUS; EVOKED-POTENTIALS; COCHLEAR NUCLEUS; HESCHLS GYRUS; PLASTICITY; auditory cortex; tinnitus; transcranial magnetic stimulation
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 15 Feb 2021 13:01
Last Modified: 15 Feb 2021 13:01
URI: https://pred.uni-regensburg.de/id/eprint/34597

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