Obed, Aiman and Schnitzbauer, Andreas A. and Bein, Thomas and Lehn, Norbert and Linde, Hans-Joerg and Schlitt, Hans J. (2006) Fatal pneumonia caused by Panton-Valentine Leucocidine-positive methicillin-resistant Staphylococcus aureus (PVL-MRSA) transmitted from a healthy donor in living-donor liver transplantation. TRANSPLANTATION, 81 (1). pp. 121-124. ISSN 0041-1337, 1534-6080
Full text not available from this repository. (Request a copy)Abstract
Severe infections arc the most dangerous complications in liver transplantation and their prevention is one of the major goals. A 60-year-old Saudi-Arabian female with decompensated hepatitis C liver cirrhosis received a right-lobe liver graft from her healthy daughter. After 9 days, the patient developed a rapidly progressive necrotizing pneumonia that was fatal in spite of extracorporal lung assist. The pneumonia was due to a Panton-Valentine Leucocidine-positive (PVL) methicillin-resistant Staphylococcus aureus (MRSA), or "community-acquired" MRSA, that had not been detectable in the patient preoperatively. The same strain of PVL-MRSA could be demonstrated in the nares of the asymptomatic donor, but not of other relatives, patients, or medical staff. These findings strongly suggest transmission of PVL-MRSA from the donor to the recipient. This case demonstrates a previously unknown, and potentially fatal, risk in living-donor liver transplantation: transmission of a severe infection from a healthy donor to the recipient.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | INFECTIONS; TRANSMISSION; RECIPIENTS; TUBERCULOSIS; EMERGENCE; living donor; liver transplantation; pneumonia; infection; methicillin-resistant Staphylococcus aureus |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 24 Feb 2021 11:23 |
| Last Modified: | 24 Feb 2021 11:23 |
| URI: | https://pred.uni-regensburg.de/id/eprint/35032 |
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