Seasonal patterns of birth in patients with glioblastoma

Koch, H. J. and Klinkhammer-Schalke, Monika and Hofstaedter, Ferdinand and Bogdahn, Ulrich and Hau, Peter (2006) Seasonal patterns of birth in patients with glioblastoma. CHRONOBIOLOGY INTERNATIONAL, 23 (5). pp. 1047-1052. ISSN 0742-0528, 1525-6073

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Abstract

Seasonal distribution of birth rates was only recently described in patients with high-grade gliomas. We analyzed 501 cases from the database of a Regional Cancer Center in Bavaria to assess annual periodicity in the birth dates of glioma patients. Prior to analysis, the number of births per month was normalized [number of births x 100,000/total number of births in Germany] to obtain birth rates per month. The approximation of the time series data by a one-year cosine model found that the glioblastoma birth rate exhibits a statistically significant annual variation, with the peak rate in January. Vitamin intake, infections, and other as-yet-unknown factors and exposures during pre- and perinatal early life may contribute to the seasonality of birth rate in patients with brain tumors.

Item Type: Article
Uncontrolled Keywords: VITAMIN-D METABOLITES; BRAIN-TUMORS; INDUCTION; ADULTS; CELLS; DEATH; RISK; glioblastoma; anaplastic astrocytoma; seasonal variation
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Neurologie
Medicine > Lehrstuhl für Pathologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 01 Mar 2021 10:49
Last Modified: 01 Mar 2021 10:49
URI: https://pred.uni-regensburg.de/id/eprint/35105

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