Hafner, Christian and Hohenleutner, Ulrich and Babilas, Philipp and Landthaler, Michael and Vogt, Thomas (2006) Targeting T cells to hit B cells: Successful treatment of cutaneous plasmacytosis with topical pimecrolimus. DERMATOLOGY, 213 (2). pp. 163-165. ISSN 1018-8665, 1421-9832
Full text not available from this repository. (Request a copy)Abstract
Cutaneous plasmacytosis is a rare disease predominantly found in Japanese patients. We describe the case of a 75-year-old white female with cutaneous plasmacytosis of the face and involvement of the bone marrow. In contrast to other cases of cutaneous plasmacytosis, the patient revealed hypogammaglobulinemia and elevated levels of free light chains in the urine. Treatment with topical pimecrolimus 1%, which primarily targets T cells, led to almost complete clinical and histological remission of the skin lesions. Our report indicates that the therapeutically induced disappearance of the plasma cells was due to indirect T-cell-mediated effects. Copyright (c) 2006 S. Karger AG, Basel
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SYSTEMIC PLASMACYTOSIS; WHITE MAN; LYMPHOMA; DISTINCT; THERAPY; ENTITY; cutaneous plasmacytosis; systemic plasmacytosis; pimecrolimus; calcineurin |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 01 Mar 2021 12:48 |
| Last Modified: | 01 Mar 2021 12:48 |
| URI: | https://pred.uni-regensburg.de/id/eprint/35137 |
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