Treatment of adductor spasticity with BTX-A in children with CP: a randomized, double-blind, placebo-controlled study

Mall, Volker and Heinen, F and Siebel, A and Bertram, C and Hafkemeyer, U and Wissel, J and Berweck, S and Haverkamp, F and Nass, G and Doderlein, L and Breitbach-Faller, N and Schulte-Mattler, Wilhelm and Korinthenberg, R (2006) Treatment of adductor spasticity with BTX-A in children with CP: a randomized, double-blind, placebo-controlled study. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 48 (1). pp. 10-13. ISSN 0012-1622,

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Abstract

Adductor spasticity in children with cerebral palsy (0) impairs motor function and development. In a placebo-controlled, double-blind, randomized multicentre study, we evaluated the effects of botulinum. toxin A (BTX-A) in 61 children (37 males, 24 females; mean age 6 years 1 month [SD 3y 1mo]) with CP (leg-dominated tetraparesis, n=39; tetraparesis, n=22; GMFCS level 1, n=3; II, n=6; 111, n=17; IV, n=29; V, n=6). Four weeks after treatment, a significant superiority of BTX-A was observed in the primary outcome measure (knee-knee distance 'fast catch', p=0.002), the Ashworth scale (p=0.001), and the Goal Attainment Scale (p=0.037).

Item Type: Article
Uncontrolled Keywords: MOTOR FUNCTION MEASURE; CEREBRAL-PALSY; THERAPY;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Neurologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 01 Mar 2021 13:24
Last Modified: 01 Mar 2021 13:24
URI: https://pred.uni-regensburg.de/id/eprint/35138

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