Malinsky, Jan and Tanner, Widmar and Opekarova, Miroslava (2016) Transmembrane voltage: Potential to induce lateral microdomains. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1861 (8). pp. 806-811. ISSN 1388-1981, 0006-3002
Full text not available from this repository. (Request a copy)Abstract
Lateral segregation of plasma membrane lipids is a generally accepted phenomenon. Lateral lipid microdomains of specific composition, structure and biological functions are established as a result of simultaneous action of several competing mechanisms which contribute to membrane organization. Various lines of evidence support the conclusion that among those mechanisms, the membrane potential plays significant and to some extent unique role. Above all, clear differences in the microdomain structure as revealed by fluorescence microscopy could be recognized between polarized and depolarized membranes. In addition, recent fluorescence spectroscopy experiments reported depolarization-induced changes in a membrane lipid order. In the context of earlier findings showing that plasma membranes of depolarized cells are less susceptible to detergents and the cells less sensitive to antibiotics or antimycotics treatment we discuss a model, in which membrane potential driven re-organization of the microdomain structure contributes to maintaining membrane integrity during response to stress, pathogen attack and other challenges involving partial depolarization of the plasma membrane. This article is part of a Special Issue entitled: The cellular lipid landscape edited by Tim P. Levine and Anant K. Menon. (C) 2016 Elsevier B.V. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | YEAST PLASMA-MEMBRANE; CANDIDA-ALBICANS; LIPID DOMAINS; SACCHAROMYCES-CEREVISIAE; ASPERGILLUS-NIDULANS; BIOLOGICAL-MEMBRANES; BUDDING YEAST; CELL BIOLOGY; LIVING YEAST; RAFTS; Membrane microdomains; Membrane structure; Lipid phase; Membrane potential; Plasma membrane; Fluorescence microscopy |
| Subjects: | 500 Science > 580 Botanical sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Pflanzenwissenschaften > Lehrstuhl für Zellbiologie und Pflanzenphysiologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 08 Apr 2019 06:24 |
| Last Modified: | 08 Apr 2019 06:24 |
| URI: | https://pred.uni-regensburg.de/id/eprint/3514 |
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