Stadlthanner, Kurt and Tome, Ana Maria and Theis, Fabian J. and Lang, Elmar W. and Gronwald, Wolfram and Kalbitzer, Hans Robert (2006) Separation of water artifacts in 2D NOESY protein spectra using congruent matrix pencils. NEUROCOMPUTING, 69 (4-6). pp. 497-522. ISSN 0925-2312, 1872-8286
Full text not available from this repository. (Request a copy)Abstract
Multidimensional proton nuclear magnetic resonance spectra of biomolecules dissolved in aqueous solutions are usually contaminated by all intense water artifact. We discuss the application of a generalized eigenvalue decomposition (GEVD) method using a matrix pencil to solve the blind source separation (BSS) problem of removing the intense solvent peak and related artifacts. The method explores correlation matrices of the signals and their filtered versions in the frequency domain and implements a two-step algebraic procedure to solve the GEVD. Two-dimensional nuclear Overhauser enhancement spectroscopy (2D NOESY) of dissolved proteins is studied. Results are compared to those obtained with the SOBI [Belouchrani et al., IEEE Trans. Signal Process. 45(2) (1997) 434-444] algorithm which jointly diagonalizes several time-delayed correlation matrices and to those of the fastICA [Hyvarinen and Oja, Neural Comput. 9 (1996) 1483-1492] algorithm which exploits higher order statistical dependencies of random variables. (c) 2005 Elsevier B.V. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | BLIND SOURCE SEPARATION; SOLVENT SUPPRESSION; NEURAL IMPLEMENTATION; 2ND-ORDER STATISTICS; RESIDUAL WATER; JADE-ALGORITHM; PROTON SPECTRA; SIGNALS; CONVOLUTION; FILTERS; blind source separation; independent component analysis; generalized eigenvalue decomposition; matrix pencil; 2D NOESY proton NMR spectra |
| Subjects: | 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Dr. Hans Robert Kalbitzer Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Elmar Lang Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Elmar Lang > Arbeitsgruppe Dr. Fabian Theis |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 03 Mar 2021 08:05 |
| Last Modified: | 03 Mar 2021 08:05 |
| URI: | https://pred.uni-regensburg.de/id/eprint/35238 |
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