Genomic structure of human omentin, a new adipocytokine expressed in omental adipose tissue

Schaffler, A and Neumeier, A and Herfarth, H and Furst, A and Scholmerich, J and Buchler, C (2005) Genomic structure of human omentin, a new adipocytokine expressed in omental adipose tissue. BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1732 (1-3). pp. 96-102. ISSN 0167-4781,

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Abstract

Genomic structure, promoter region, amino acid sequence and exon-specific primer combinations of the human omentin gene are presented. Omentin mRNA expression differs between omental adipose tissue probes from patients with chronic inflammatory bowel diseases such as Crohn's disease. Sequence comparisons revealed a 100% identity of omentin with human intelectin. Based on this, omentin might be a new adipocytokine playing a role in the defense against intestinal bacterial translocation in the context of Crohn's disease. (c) 2005 Elsevier B.V. All rights reserved.

Item Type: Article
Uncontrolled Keywords: METABOLIC SYNDROME; EMERGING ROLE; VISCERAL FAT; DISEASE; INFLAMMATION; PROTEIN; ADIPONECTIN; ADIPOKINES; MECHANISMS; omentin; intelectin; adipocyte; chronic inflammatory bowel disease; Crohn's disease
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Chirurgie
Medicine > Lehrstuhl für Innere Medizin I
Depositing User: Dr. Gernot Deinzer
Date Deposited: 04 Mar 2021 09:44
Last Modified: 04 Mar 2021 09:44
URI: https://pred.uni-regensburg.de/id/eprint/35304

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