Baumann, Rosemarie and Dragon, S. (2005) Erythropoiesis and red cell function in vertebrate embryos. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 35. pp. 2-12. ISSN 0014-2972, 1365-2362
Full text not available from this repository. (Request a copy)Abstract
All vertebrate embryos produce a specific erythroid cell population - primitive erythrocytes - early in development. These cells are characterized by expression of the specific embryonic haemoglobins. Many aspects of primitive erythropoiesis and the physiological function of primitive red cells are still enigmatic. Nevertheless, recent years have seen intensive efforts to characterize in greater detail the molecular events underlying the initiation of erythropoiesis in vertebrate embryos. Several key genes have been identified that are necessary for primitive and the subsequent definitive erythropoiesis, which differs in several aspect from primitive erythropoiesis. This review gives in its first part a short overview dealing with comparative aspects of primitive and early definitive erythropoiesis in higher and lower vertebrates and in the second part we discuss the physiological function of primitive red cells based mainly on results from mammalian and avian embryos.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | BONE MORPHOGENETIC PROTEIN-4; CARBONIC-ANHYDRASE ACTIVITY; SURFACE HISTIDYL RESIDUES; HEMATOPOIETIC STEM-CELLS; NORMAL ADULT HEMOGLOBIN; YOLK-SAC; OXYGEN-TRANSPORT; CHICK-EMBRYO; BLOOD-ISLAND; PRIMITIVE ERYTHROPOIESIS; BMP; VEGF; GATA; erythropoietin; oxygen affinity |
| Subjects: | 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Physiologie > Alumni or Retired > Prof. Dr. Rosemarie Baumann |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 12 Apr 2021 12:47 |
| Last Modified: | 12 Apr 2021 12:47 |
| URI: | https://pred.uni-regensburg.de/id/eprint/35345 |
Actions (login required)
 |
View Item |
