Szeimies, Rolf-Markus and Morton, Colin A. and Sidoroff, Alexis and Braathen, Lasse R. (2005) Photodynamic therapy for non-melanoma skin cancer. ACTA DERMATO-VENEREOLOGICA, 85 (6). pp. 483-490. ISSN 0001-5555
Full text not available from this repository. (Request a copy)Abstract
Photodynamic therapy is a treatment modality that has been shown to be effective mainly for the dermatooncologic conditions: actinic keratosis, Bowen's disease, in situ squamous cell carcinoma and basal cell carcinoma. Recent work has focused on the development and evaluation of topical photosensitizers like the haem precursor 5-aminolevulinic acid or its methyl ester, both inducing photosensitizing porphyrins. These drugs do not induce strong generalized cutaneous photosensitization, unlike the systemically applied porphyrins or their derivatives. For dermatological purposes incoherent lamps or light-emitting diode arrays can be used for light activation. Cure rates reported for very superficial lesions ( tumour thickness <2 - 3 mm) are comparable to those achieved by other therapeutic modalities. Photodynamic therapy is a minimally invasive therapy associated with excellent cosmetic results. For actinic keratosis and basal cell carcinoma, methyl aminolevulinate-photodynamic therapy is already approved in Europe, Australia and New Zealand, and is now also approved for actinic keratosis in the US.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | BASAL-CELL CARCINOMAS; TOPICAL METHYL AMINOLEVULINATE; 5-AMINOLEVULINIC ACID METHYLESTER; BOWENS-DISEASE; ACTINIC KERATOSES; IN-VIVO; SOLAR KERATOSES; LIGHT; TRIAL; LASER; photodynamic therapy; fluorescence detection; aminolevulinic acid; methyl aminolevulinate; skin cancer |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 22 Jun 2022 11:57 |
| Last Modified: | 22 Jun 2022 11:57 |
| URI: | https://pred.uni-regensburg.de/id/eprint/35439 |
Actions (login required)
 |
View Item |
