Antibacterial photodynamic therapy. A new treatment for bacterial skin diseases?

Maisch, Tim and Szeimies, R.-M. and Lehn, N. and Abels, C. (2005) Antibacterial photodynamic therapy. A new treatment for bacterial skin diseases? HAUTARZT, 56 (11). pp. 1048-1055. ISSN 0017-8470, 1432-1173

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Abstract

The basis of "antibacterial photodynamic therapy" involves the killing of bacteria by reactive oxygen species in the presence of a photosensitizer and light. Possible dermatologic indications include inactivation of bacteria in skin and wound infections and reduction in density of nosocomial multiresistant infections. The chief advantage of antibacterial photodynamic therapy is that regardless of the resistance pattern of a bacteria, inactivation can be achieved, analogous to the use of antiseptics. The aim of the present review is to describe the physicochemical and biological mechanisms of antibacterial photodynamic therapy as well as possible clinical indications in dermatology.

Item Type: Article
Uncontrolled Keywords: RESISTANT STAPHYLOCOCCUS-AUREUS; OUTER-MEMBRANE PERMEABILITY; GRAM-POSITIVE BACTERIA; ESCHERICHIA-COLI; IN-VIVO; SALMONELLA-TYPHIMURIUM; SINGLET OXYGEN; ACNE-VULGARIS; AMINOLEVULINIC-ACID; ATOPIC-DERMATITIS; MRSA; PDT; reactive oxygen species; acne vulgaris; wound healing
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Dermatologie und Venerologie
Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Depositing User: Petra Gürster
Date Deposited: 22 Jun 2022 11:42
Last Modified: 22 Jun 2022 11:42
URI: https://pred.uni-regensburg.de/id/eprint/35467

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