Zorger, Niels and Volk, Markus and Hamer, Okka W. and Lenhart, Markus and Seitz, Johannes and Butz, Bernhard and Paetzel, Christian (2005) Intraarterial gadolinium-enhanced MR angiography in humans for the detection of infrainguinal arterial stenoses before and after percutaneous angioplasty. AMERICAN JOURNAL OF ROENTGENOLOGY, 185 (4). pp. 867-872. ISSN 0361-803X,
Full text not available from this repository.Abstract
OBJECTIVE. The objectives of this study were to show the feasibility of intraarterial MR angiography of the infrainguinal arteries and to compare the accuracy of intraarterial MR angiography with selective intraarterial digital subtraction angiography for the detection of stenoses before and after percutaneous balloon angioplasty. SUBJECTS AND METHODS. Fifteen patients underwent digital subtraction angiography and intraarterial MR angiography before and after balloon angioplasty. For intraarterial MR angiography, 30 mL of diluted contrast agent (5 mL of gadodiamide diluted in 55 mL of 0.9% saline solution) was injected through a sheath in the superficial femoral artery using a flow rate of 2.5 mL/sec. A 3D gradient-echo sequence was performed. Four independent blinded observers assessed differences in the quantitative measurement of stenoses and localization of lesions between digital subtraction angiography and intraarterial MR angiography. The overall impression of the intraarterial MR angiography images was documented on a 4-point scale (1 = excellent, 4 = poor). Interobserver variability was calculated. RESULTS. Intraarterial MR angiography from the upper leg to the trifurcation was feasible in all 30 examinations with a mean overall impression of all segments of 1.3 (SD, 0.68). For the detection of significant stenoses ( >= 50% stenosis), the overall sensitivity and specificity for the femoropopliteal and crural vessels were 92.4% and 91.7% and 91.9% and 87.8%, respectively. For the complete leg, sensitivity and specificity were 92.2% and 88.6%, respectively. Interobserver variability for intraarterial MR angiography of the crural vessels exceeded that of the femoropopliteal arteries. CONCLUSION. Intraarterial MR angiography of the infrainguinal arteries is feasible in humans using injections of diluted contrast agent at concentrations as low as 8%. It has a high sensitivity for detecting stenoses and an acceptable interobserver variability.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | DIGITAL SUBTRACTION ANGIOGRAPHY; LOWER-EXTREMITY; CONTRAST AGENT; ARTERIOGRAPHY; FEASIBILITY; DISEASE; MEDIA; TABLE; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 26 Apr 2021 07:04 |
| Last Modified: | 26 Apr 2021 07:04 |
| URI: | https://pred.uni-regensburg.de/id/eprint/35542 |
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