Dorenbeck, Ulrich and Grunwald, I. Q. and Schlaier, Juergen and Feuerbach, Stefan (2005) Diffusion-weighted imaging with calculated apparent diffusion coefficient of enhancing extra-axial masses. JOURNAL OF NEUROIMAGING, 15 (4). pp. 341-347. ISSN 1051-2284,
Full text not available from this repository. (Request a copy)Abstract
Background and Purpose. Sometimes intracranial contrast-enhancing tumors like meningiomas, metastases, lymphomas, and schwannomas can mimic each other. It was the aim of the present study to investigate if intracranial contrast-enhancing lesions can be reliably differentiated with the help of diffusion-weighted imaging with calculated apparent diffusion coefficients (ADCs). Methods. 29 patients (ages ranging from 22 to 82 years, mean age of 58.6 years) were included. Nine meningiomas, 7 metastases, 6 lymphomas, and 7 schwannomas were investigated. The ADC value in the lesions and in the perifocal edema was analyzed. Results. For the lymphomas, the authors measured the lowest ADC values in the contrast-enhancing part (0.59 +/- 0.09 x 10(-3) mm(2)/sec). The meningiomas showed a mean ADC value of 0.98 +/- 0.18 x 10(-3) mm(2)/sec. The schwannomas and metastases showed higher ADC values of 1.33 +/- 0.28 x 10(-3) mm(2)/sec and 1.05 +/- 0.20 x 10(-3) mm(2)/sec. The authors saw a statistically significant difference between lymphomas, meningiomas, and metastases concerning the ADC values in the contrast-enhancing part. Conclusions. In spite of a small sample size and partly a wide range of values, the authors found statistically significant differences between meningiomas, metastases, and lymphomas concerning ADC values. Nevertheless, a differentiation of these lesions only with the help of ADC values seems questionable.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MR; TUMORS; MENINGIOMAS; LYMPHOMA; magnetic resonance imaging; diffusion-weighted imaging; brain tumors |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurochirurgie Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 26 Apr 2021 11:58 |
| Last Modified: | 26 Apr 2021 11:58 |
| URI: | https://pred.uni-regensburg.de/id/eprint/35596 |
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