Berg, Christoph and Geipel, A. and Kohl, T. and Smrcek, J. and Germer, Ute and Baschat, A. A. and Hansmann, M. and Gembruch, U. (2005) Fetal echocardiographic evaluation of atrial morphology and the prediction of laterality in cases of heterotaxy syndromes. ULTRASOUND IN OBSTETRICS & GYNECOLOGY, 26 (5). pp. 538-545. ISSN 0960-7692,
Full text not available from this repository. (Request a copy)Abstract
Objective To evaluate whether abnormal atrial morphology, which is well recognized in autopsy series, is detectable by fetal echocardiographic examination of the four-chamber view, and can therefore be utilized to differentiate left from right isomerism in heterotaxy syndromes. Methods This study was a retrospective review of 30 cases with prenatally diagnosed heterotaxy syndromes. Ultrasound video recordings and still images were reviewed with respect to atrial morphology in the four-chamber view. In 25 cases the morphology of both atria was sufficiently well visualized on the recordings to be evaluated and only these were included in the study. Results Two types of atrial morphology were distinguished in our cohort: a sickle-shape with the tip pointing laterally and apically, and a blunt shape resembling the usual atrial appearance in the four-chamber view. Nineteen out of the 25 cases (76%) presented with isomerism of the atria in the four-chamber view. Thirteen bad bilateral sickle-shaped atrial morphology, all associated with left isomerism. Six had bilateral blunt-shaped atrial morphology, all associated with right isomerism. The atria of the remaining six cases were not isomeric, the right atrium being sickle-shaped and the left blunt-shaped. Five of the latter cases were associated with left and one with right isomerism. Conclusions The majority of prenatally diagnosed heterotaxy syndromes seem to present with isomeric atrial morphology in the four-chamber view. In these cases a differentiation between left and right isomerism can be based on the two distinct types of atrial morphology. This may further enhance the prenatal differentiation of these syndromes. Copyright (c) 2005 ISUOG. Published by John Wiley & Sons, Ltd.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | COMPLETE HEART-BLOCK; ATRIOVENTRICULAR-BLOCK; ISOMERISM; DIAGNOSIS; POLYSPLENIA; EXPERIENCE; ASPLENIA; LIFE; MANAGEMENT; PROGNOSIS; atrial morphology; echocardiography; fetus; heterotaxy; isomerism; prenatal diagnosis |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Frauenheilkunde) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 27 Apr 2021 07:34 |
| Last Modified: | 27 Apr 2021 07:34 |
| URI: | https://pred.uni-regensburg.de/id/eprint/35619 |
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