Schaeffler, Andreas and Binart, N. and Schoelmerich, Juergen and Buechler, Christa (2005) Hypothesis paper brain talks with fat - evidence for a hypothalamic-pituitary-adipose axis? NEUROPEPTIDES, 39 (4). pp. 363-367. ISSN 0143-4179,
Full text not available from this repository. (Request a copy)Abstract
The adipose tissue signals to the brain via its secretory products. However, it is unknown whether the brain itself can directly contact the fat tissue. In order to test this hypothesis, the adipocytic expression of receptors for pituitary hormones and hypothalamic peptides was investigated. Besides FSH- and LH-receptors, adipocytes do express the specific receptors for ACTH, TSH, GH, prolactin, oxytocin and the three receptor subtypes for vasopressin. Thus, the adipose tissue might no longer be regarded as an inert and steady tissue but as a fast acting player downstream of and under the control of the brain. Based on this, the potential existence and clinical impact of a hypothalamic pituitary-adipose axis should further be investigated. (c) 2005 Published by Elsevier Ltd.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | EXPRESSION; pituitary; hypothalamus; adipocyte; hormone; receptor |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 03 May 2021 11:50 |
| Last Modified: | 03 May 2021 11:50 |
| URI: | https://pred.uni-regensburg.de/id/eprint/35840 |
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