Synthetic approaches towards structurally diverse gamma-butyrolactone natural-product-like compounds

Seitz, Michael and Reiser, Oliver (2005) Synthetic approaches towards structurally diverse gamma-butyrolactone natural-product-like compounds. CURRENT OPINION IN CHEMICAL BIOLOGY, 9 (3). pp. 285-292. ISSN 1367-5931, 1879-0402

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Abstract

Natural products containing a gamma-butyrolactone ring are abundant in nature; however, few general synthetic approaches to their stereoselective synthesis with broad structural variety are known. In this article, recent developments towards mono- and polycyclic gamma-butyrolactone natural products and analogs are discussed. A special focus is given to asymmetric methods applying transition metal or organocatalysts that allow not only the efficient introduction of a broad variety of functional groups but ideally also the flexible construction of various natural-product-like, polycyclic scaffolds from common precursors.

Item Type: Article
Uncontrolled Keywords: ENANTIOSELECTIVE TOTAL-SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; CATALYZED CYCLOCARBONYLATION; PARACONIC ACIDS; LACTONES; LIBRARIES; ALDEHYDES; KETONES; (+)-BLASTMYCINONE; DIAZOACETATES
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser
Depositing User: Petra Gürster
Date Deposited: 23 Mar 2022 07:51
Last Modified: 23 Mar 2022 07:51
URI: https://pred.uni-regensburg.de/id/eprint/36036

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