The Influence of Preoperative Aneurysmal Thrombus Quantity and Distribution on the Development of Type II Endoleaks with Aneurysm Sac Enlargement After EVAR of AAA

Mueller-Wille, R. and Guentner, O. and Zeman, F. and Dollinger, M. and Halg, C. and Beyer, L. P. and Pfister, K. and Kasprzak, P. and Stroszczynski, C. and Wohlgemuth, W. A. (2016) The Influence of Preoperative Aneurysmal Thrombus Quantity and Distribution on the Development of Type II Endoleaks with Aneurysm Sac Enlargement After EVAR of AAA. CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 39 (8). pp. 1099-1109. ISSN 0174-1551, 1432-086X

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Abstract

To determine the influence of preoperative aneurysmal thrombus quantity and distribution on the development of type II endoleak with aneurysm sac enlargement after endovascular aneurysm repair (EVAR). We retrospectively analyzed the pre- and postoperatively performed CT scans of 118 patients who had follow-up imaging for at least 1 year after EVAR available. We assessed preoperative thrombus perimeter (T (Peri)), diameter (T (Dia)), cross-sectional area (T (CSA)), and volume (T (Vol)). The preoperative thrombus distribution was classified into no thrombus, semilunar-shaped (anterior, right side, left side, posterior) thrombus, and circumferential type thrombus. The number of preoperative patent aortic side branches (ASB) was identified. Endpoint was type II endoleak with aneurysm volume (A (Vol)) increase of a parts per thousand yen5 % during follow-up. During follow-up (2 years, range 1-9 years), 17 patients with type II endoleak had significant A (Vol) increase. Less preoperative T (Peri), T (Dia), T (CSA), and T (Vol) were associated with A (Vol) increase. A circumferential thrombus distribution significantly protected against aneurysm enlargement (p = 0.028). The variables with the strongest significance for A (Vol) increase were preoperative T (Vol)/A (Vol) ratio (OR 0.95; p = 0.037) and number of patent ASB (OR 3.52; p < 0.001). A low preoperative T (Vol)/A (Vol) ratio and a high number of patent ASB were associated with aneurysm sac enlargement after EVAR.

Item Type: Article
Uncontrolled Keywords: ABDOMINAL AORTIC-ANEURYSMS; INFERIOR MESENTERIC-ARTERY; ENDOVASCULAR REPAIR; RISK-FACTORS; PREDICTIVE FACTORS; INTRASAC THROMBUS; VOLUME; IMPACT; LOAD; ANTICOAGULATION; Cardiovascular diseases; Vascular diseases; Aneurysm; Endoleak; Blood vessel prosthesis
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Abteilung für Gefäßchirurgie
Medicine > Lehrstuhl für Röntgendiagnostik
Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien
Depositing User: Dr. Gernot Deinzer
Date Deposited: 08 Apr 2019 08:08
Last Modified: 08 Apr 2019 08:08
URI: https://pred.uni-regensburg.de/id/eprint/3607

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