Bein, Thomas and Scherer, Markus N. and Philipp, Alois and Weber, Frank and Woertgen, Chris (2005) Pumpless extracorporeal lung assist (Pecla) in patients with acute respiratory distress syndrome and severe brain injury. JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 58 (6). pp. 1294-1297. ISSN 1079-6061
Full text not available from this repository. (Request a copy)Abstract
Background. A retrospective analysis was performed to estimate the practicability of a pumpless extracorporeal lung assist system (pECLA) in trauma patients suffering from severe brain injury and the acute respiratory distress syndrome (ARDS). Methods: Five patients with acute severe brain injury and ARDS, ventilated in a lung protective mode, were connected to pECLA to avoid the detrimental effects of hypercapnia on intracranial pressure (ICP) and cerebral outcome. With pECLA hyper-capnia was eliminated in all patients while the minute volume of artificial ventilation could be reduced. Subsequently, ICP was reduced, systemic hemodynamics and cerebral perfusion pressure remained stable. One patient died due to multi-organ failure as a consequence of multi-trauma. The remaining patients survived showing a good neurologic function. Conclusions: pECLA is a promising alternative compared with conventional pump-driven systems for patients with ARDS and brain injury, since the pECLA system has minor restrictions, limitations and side effects.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HEAD-INJURY; acute respiratory distress syndrome; acute brain injury; extracorporeal lung assist hypercapnia; intracranial pressure |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Anästhesiologie Medicine > Lehrstuhl für Chirurgie Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie Medicine > Lehrstuhl für Neurochirurgie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 23 Mar 2022 07:49 |
| Last Modified: | 23 Mar 2022 07:49 |
| URI: | https://pred.uni-regensburg.de/id/eprint/36080 |
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