Hafner, C and Linde, HJ and Vogt, T and Breindl, G and Tintelnot, K and Koellner, K and Landthaler, M and Szeimies, RM (2005) Primary cutaneous cryptococcosis and secondary antigenemia in a patient with long-term corticosteroid therapy. INFECTION, 33 (2). pp. 86-89. ISSN 0300-8126,
Full text not available from this repository. (Request a copy)Abstract
We report a case of a 71-year-old male who developed severe cellulitis of his right forearm and hand after he had an accidental injury from the sharp edge of a metal plate of a birdhouse. The patient suffers from chronic asthma and has been treated with systemic corticosteroids for years. Culture of aspirates from two sites of the wound area revealed growth of Cryptococcus neoformans in one and Acinetobacter lwoffii in the other. After combined treatment including antibiotics, antifungal therapy with fluconazole 400 mg/d and surgical debridement followed by a mesh graft, the patient achieved complete healing of the wound. Five months after the infection, the patient was still positive for cryptococcal antigen at a titer of 1:64 despite oral treatment with fluconazole 50 mg/d, and maintenance therapy with fluconazole 200 mg/d was recommended for 6 months, or Longer depending on further results. The clinical and microbiological characteristics of this patient as well as therapeutical and epidemiological aspects of primary cutaneous cryptococcosis (PCC) are discussed.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | NEOFORMANS VAR NEOFORMANS; NECROTIZING FASCIITIS; SEROTYPE-D; IMMUNOCOMPETENT; DROPPINGS; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Plastische-, Hand- und Wiederherstellungschirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 17 May 2021 13:11 |
| Last Modified: | 17 May 2021 13:11 |
| URI: | https://pred.uni-regensburg.de/id/eprint/36303 |
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