Paper, Dietrich H. and Karall, Elisabeth and Kremser, Michaela and Krenn, Liselotte (2005) Comparison of the antiinflammatory effects of Drosera rotundifolia and Drosera madagascariensis in the HET-CAM assay. PHYTOTHERAPY RESEARCH, 19 (4). pp. 323-326. ISSN 0951-418X, 1099-1573
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The antfinflammatory effects of ethanol and aqueous extracts from Drosera rotundifolia and from Drosera madagascariensis were compared in vivo in the HET-CAM assay. Both extracts from D. rotundifolia and the ethanol extract from D. madagascariensis showed remarkable efficacy at doses of 500 mu g/pellet. The inhibition of the inflammation by the extracts was stronger than that by 50 mu g hydrocortisone/pellet. In contrast, there was only a very weak effect observed at a dose of 500 mu g/pellet of the water extract from D. madagascariensis. The chemical analyses of the extracts showed that the effect cannot be attributed to naphthoquinones, but might be due to flavonoids. Ellagic acid obviously plays an important role in the antiangiogenic effect of the Drosera extracts. Copyright (c) 2005 John Wiley & Sons, Ltd.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | NAPHTHOQUINONES; EXTRACTS; HERBA; antiinflammatory activity; HET-CAM; Drosera sp.; flavonoids; ellagic acid; naphthoquinones |
| Subjects: | 600 Technology > 615 Pharmacy |
| Divisions: | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Biology (Prof. Heilmann) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 18 May 2021 09:15 |
| Last Modified: | 18 May 2021 09:15 |
| URI: | https://pred.uni-regensburg.de/id/eprint/36336 |
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