Management of erosive lichen planus with topical tacrolimus and recurrence secondary to metoprolol

Meyer, S. and Burgdorff, T. and Szeimies, Rolf-Markus and Vogt, T. and Landthaler, Michael and Karrer, Sigrid (2005) Management of erosive lichen planus with topical tacrolimus and recurrence secondary to metoprolol. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 19 (2). pp. 236-239. ISSN 0926-9959, 1468-3083

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Abstract

Metoprolol, a widely prescribed beta-adrenergic receptor blocker, has occasionally been associated with a diversity of cutaneous reactions. We present a 79-year-old male patient with erosive lichen planus (LP) on the feet and hands who was successfully treated with topical tacrolimus. Six months after the lesions had been cured the patient received the beta-receptor blocker metoprolol for the treatment of hypertonus. Within only 2 weeks of metoprolol intake the erosive lesions on the palms and feet recurred. After discontinuation of the drug and repetitive topical treatment with tacrolimus a complete remission of the lesions could be achieved. The recurrence of erosive LP probably secondary to metoprolol and the therapeutic success of topical tacrolimus in the treatment of LP are discussed.

Item Type: Article
Uncontrolled Keywords: ATOPIC-DERMATITIS; DRUG; PATHOGENESIS; cutaneous side-effects; beta-receptor blockers; erosive lichen planus; FK506; tacrolimus
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Dermatologie und Venerologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 21 May 2021 11:10
Last Modified: 21 May 2021 11:10
URI: https://pred.uni-regensburg.de/id/eprint/36435

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